Crohn’s Disease

Crohn’s Disease Overview

Crohn’s disease is a chronic, inflammatory bowel ailment affecting the digestive tract lining and can sometimes lead to fatal health complications. Symptoms typically associated with Crohn’s includes anemia, fatigue, diarrhea, weight loss and abdominal pain. While some people living with Crohn’s may be symptom-free, many others experience consistent severe symptoms. Though a rare and incurable disease, Crohn’s affects less than 200,000 patients each year in the U.S. with only medication or surgery as treatment options[84].

Cannabinoid Use for Inflammatory Bowel Disease

Cannabinoids as a potential therapeutic option for inflammatory bowel disease (IBD) gradually gain popularity. Studies conclude that the endocannabinoid system (ECS) emits therapeutic effects in mouse colitis and plays a significant role in how IBD affects the body. Reports detail discoveries of possible systematic IBD treatment with cannabinoids. A considerable number of IBD patients with severe complications use cannabinoids to alleviate symptoms of nausea, pain, appetite and improvement of mood[85].

Case Developments

Scientists continue to conduct extensive, double-blind, randomized, placebo-controlled tests with the use of biopsy findings, endoscopic disease severity, and serial inflammatory markers, to objectively prove how cannabinoids like CBD improves IBD to the point of recommended and practical application[85]. Completed studies publish how cannabinoids display significant potential as an organic, novel anti-inflammatory factor with specific targeting of CB2 receptors providing potential mediating immunosuppressive effects without any adverse, psychotropic side effects[86].

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