Approximately 200,000 people of all ages within the United States are living with epilepsy. It’s a chronic disorder resulting from genetics or brain injuries like a stroke or trauma. Throughout life, people battling with epilepsy experience abnormal symptoms, sensations, and behavior which can even consist of loss of consciousness. Most common symptoms are seizures caused by disturbed nerve cell activity in the brain. Combinations of different prescriptions and high doses have resulted in more severe side effects especially for people with epilepsies resistant to treatments.
Endocannabinoid Activity Against Seizures
For years, clinical evidence validates cannabinoids like CBD reduces seizures particularly in those living with treatment-resistant epilepsy. Published reports show how natural endocannabinoid release within the body can prevent seizure-induced neurotoxicity. These studies demonstrate how cannabinoids are efficient against seizures and reduce epilepsy-related mortality. Further investigations illustrate how chronic seizures trigger dynamic changes within the endocannabinoid system to regulate and maintain acute and chronic balance. Ongoing research has brought new awareness to CBD’s future treating epilepsy, neuropsychiatric disorders, neuronal injury, and psychiatric diseases.
A particular study published in Epilepsia indicated that CBD does indeed possess anti-seizure properties for successfully treating individuals with epilepsy . Another investigation in 2013 surveyed 19 parents with children diagnosed with Dravet Syndrome and experiencing treatment-resistant epilepsies using products with high-concentrated CBD. Though results varied, nearly half the children had an 80% reduction in seizure frequency, and approximately 10% were completely seizure-free. Other effects reported by the parents include better mood, increased alertness, and improved sleep.
New studies have successfully shown a substantial decrease in seizure frequency and in some cases, complete freedom of seizures once treated with CBD. A more recent case involved 75 patients who moved to Colorado for cannabinoid-extract treatment. Through oral administration, the cannabinoids controlled seizures in over half the patients and even reduced seizures by over 50% with a third of tested patients .