What Is SaffSerene and How Does It Work?

What Is SaffSerene and How Does It Work?

Learn how SaffSerene saffron boosts mood, helps relieve stress, and other benefits to your health and wellness. Especially when combined with CBD for improved calm.

SaffSerene is a new and key player in our mood-enhancing CBD Calming Capsules. So, we are here to answer your questions today about this form of saffron, and how this powerful mood-supporting botanical can bring mental and physical health benefits to your daily life.

Today, we’re shining the spotlight on SaffSerene, the standardized saffron extract we use in our new Calming Capsules to help with mood balance and stress support.

Key points


  • What is SaffSerene? Is it the same as saffron?
  • Where does it come from?
  • What are SaffSerene benefits?
  • Where can you find SaffSerene?


You may not have heard of SaffSerene, specifically, but you may already be familiar with where it comes from: the Crocus sativus L. flowering plant that we commonly call saffron. But did you know this plant has a very important use in your health and wellness routine? We think this is big news for CBD users and for folks who are actively searching for natural solutions to daily health and wellness issues.

Let’s get to know this “SaffSerene,” which sounds a little “groovy” right? Like saffron + serenity = magic bubbles in a meadow or something. As cool as it sounds, it's more than just a fancy name you can throw around to impress your health-conscious friends. You’ll also want to know a little about what it really is and how it works.

Today, we’ll show you how SaffSerene saffron helps to boost your daily mood along with a laundry list of other helpful health benefits. And, that the magic really happens when you combine it with power-duo ashwagandha and CBD!

First, let’s take a look at saffron, in general, and then why we’ve chosen to use SaffSerene saffron in our new Calming Capsules.

What Is Saffron?

Saffron is a flowering plant, also called autumn crocus, that is a member of the Iridaceae family and grows in dry climates with bright, stunning purple flowers. We take extracts from this breathtaking plant to use for culinary or for health and wellness purposes, and people have done so for centuries.


A wooden scooper with saffron it it with saffron in a container behind it as well as saffron being scattered around everywhere


Saffron, Crocus sativus L, grows most commonly in Iran, Greece, Spain, Italy, Turkey, Pakistan, Azerbaijan, China, Egypt, Morocco, and India. It's used as a lightly sweet and fragrant cooking spice, a natural food coloring, and textile dye, but also as a botanical extract for health and wellness. Currently, there are all kinds of scientific studies to analyze saffron’s effects on brain health and to determine the roots of its psychological effects.

You may have heard of saffron from supplements combining rhodiola extract with saffron extracts, or have seen it as rhodiola SaffSerene saffron extract. You may have also seen it in supplements that also contain vitamin B6 (as P5P), magnesium bisglycinate, and/or taurine. There are a variety of botanical extracts that target psychological well-being.

SaffSerene is one of these extracts that uses the power of saffron to deliver mood-boosting benefits. Recently here at cbdMD, we’ve begun using this powerful herb as an additional ingredient to include with our proprietary CBD blends to give you the best in calming care for mind and body.

Though there may be a lot of contenders on the market, we have a new blend that rises above them all: SaffSerene saffron, Sensoril, and the powerful proprietary CBD blend of cannabinoids and terpenes.

What Is SaffSerene?

SaffSerene is a branded form of the botanical extract of saffron. SaffSerene is used primarily as a calming agent in wellness supplements such as our new Calming Capsules, which also contain other relaxing ingredients – Sensoril (ashwagandha) and CBD extracts.

Branding and standardizing this form of saffron allows clinical studies as well as studies on efficacy, potency, application, etc. to be more precise, as there are many forms of saffron originating from a variety of countries and growing processes. We chose one form to use to create products that help you manage stress and maintain a healthy mood balance.

SaffSerene Benefits

SaffSerene can be categorized as a mood-enhancing supplement that helps you manage stress, improve energy levels, and gain inner support for your psychological well-being. But there are more beneficial effects, such as:


  • Helps support healthy mood balance.
  • Supports a balanced response to stress.
  • Helps support a positive mental outlook.
  • Maintains a healthy psychological well-being.
  • Promotes healthy psychological function.
  • Helps support healthy eating habits.
  • Naturally suppresses appetite.
  • Helps support nervous system health.
  • Helps support healthy stress levels for those living a stressful lifestyle.


Components of Saffron: Safranal, Crocin, and Picrocrocin

Likely the reason saffron is so useful as a health and wellness supplement is the components in saffron that each provide a different type of benefit. You may see these terms used, so here’s what you need to know about each of saffron’s components: safranal, crocin, and picrocrocin.

What Is Safranal?

The main component of saffron is called safranal and is derived from the stigmas of the Crocus sativus flowers. (Those are the orange, spindly things sticking out of the flowers.) This fragrant component is the one most hailed for positive neuropsychological effects, making it the part of saffron with the most beneficial effects on mood and psychological function.

What Is Crocin?

Crocin is a water-soluble carotenoid in the Crocus sativus plant. (These carotenoids give the lovely orange hue to the stigmas.) Crocin is the component that provides antioxidant effects, increases blood flow, and helps with the positive effects on the nervous system.

What Is Picrocrocin?

Picrocrocin is a beta-D glucoside and precursor of safranal. It gives the saffron spice a pungent or bitter taste. But what excites us most about this component of saffron is how it affects the appetite. As you are likely well aware, mood imbalances often adversely affect the appetite, coining the term “eating your feelings” or “mood eating.”

Mood shifts prompt you to eat more when bored, feeling stressed, etc. Picocrocin is the part of saffron that helps improve digestion and helps the mood-eater to physically stabilize, in addition to the mood-stabilizing effects of other parts of the saffron plant.

Additional Calming Botanical Ingredients

To provide more well-rounded calming support, we’ve elected to combine saffron with other botanical ingredients for the most mood-enhancing support possible. If you have issues with daily stress, mood swings, and/or sleep disruptions due to stress or discomfort, then the Calming Capsules are formulated just for you.

Many people who take CBD products regularly do so in hopes of feeling more calm, improving how their minds move through the day and how their bodies and minds react to stress – all very worthy wellness goals. And now, there’s one more way to provide this type of support: by pairing SaffSerene with ashwagandha and CBD for a trifecta of calming support.

Note: SaffSerene or CBD products are not intended to diagnose, treat, cure, or prevent any disease. Please consult a medical doctor or healthcare practitioner for any diagnoses and treatments they may recommend and before beginning any form of dietary supplement.

Sensoril (Ashwagandha)

Similarly, Sensoril, the branded ashwagandha ingredient we use in our products, has mood effects that can also be of benefit. Here are some of the health and mood enhancements of this botanical extract:


  • Manages and reduces stress.
  • Improves mental cognitive health, mood, fatigue, and vitality.
  • Improves focus and reaction time.
  • Improves acute discomfort.
  • Increases stress tolerance and resilience to stress.
  • Provides positive support for mental health and well-being.
  • Reduces stress-induced sleep disruption.


CBD (Cannabidiol)

CBD, our powerhouse ingredient, also provides support for users of SaffSerene by way of a generalized support system and homeostasis within the bodily systems. This overall health booster is the perfect partner in a calming support supplement.

CBD, which is the shortened term for cannabidiol, one of the phytocannabinoids sourced from USA-grown industrial hemp, contributes by:


  • Providing a greater sense of calm.
  • Supporting a healthy sleep cycle.
  • Working with the body’s endocannabinoid system to help bodily systems work more efficiently.
  • Easing common discomforts.


Where Can You Get SaffSerene Saffron?

When SaffSerene saffron is included in a particular CBD product at cbdMD, it will be notated on the products page and also on the ingredients list for the product. When a product is marked “calming” please note which calming ingredients are used in that particular product, as we have a variety of them in a variety of products so you can find what works best for you.

Calming Capsules with SaffSerene

New Calming Capsules, 750 mg, are an easy way to bring more calm to your daily life, support nervous system health, and to help you manage healthy stress levels.


A pile of capsules clumped together


What Else Is in the Calming Capsules?

Calming Capsules contain SaffSerene, Sensoril (Ashwagandha), CBD (Cannabidiol), and CBG (Cannabigerol). They are a vegan and gluten-free option for calming support.

For More Information on Calming Support

Aside from these new SaffSerene Calming Capsules, we have a wide variety of calming support products here at cbdMD. From sleep aids to supportive gummies, there’s a calming helper that’s right for you. You can take a brief “Find Your Product” quiz on our website, but here are a few suggestions:

For Help with Sleep

Sleep is a critical function of the body. This is when the cells of the body go into repair mode, digestion is hard at work, and the mind and body relax after combatting various sources of stress throughout the day.

Without sleep, your body and mind will cease to function properly and you could go from being stressed-out to downright ill. Because sleep is so important to your physical and mental health, we have a variety of sleep aids to help you get the reparative and restorative sleep your body and mind need.

CBD Tinctures for Sleep come in two concentrations: 500 mg and 1500 mg. Both of them contain melatonin, an essential sleep-inducing hormone your body needs.

CBD Softgel Capsules for Sleep come in three concentrations, all of which also contain melatonin: 500 mg, 1000 mg, and 1500 mg.

Sleep-Aid Gummies come with melatonin, ashwagandha, and 750 mg of CBD.

CBD Bath Salts for Sleep (with Dead Sea, Himalayan, and Epsom salts, as well as melatonin) help you to wind down after a long and stressful day: 100 mg, 500 mg.

For Help with Calm and Stress

In addition to SaffSerene Calming Capsules, there are stress-busting CBD products such as tinctures, CBD softgels, CBD gummies, and a variety of bath and body CBD products infused with calming lavender.


  • CBD Tinctures for daily stress support.
  • CBD Softgels for daily stress support.
  • CBD Gummies for on-the-go or as-needed stress relief. Check out our Calming Gummies with ashwagandha!
  • CBD Lavender Chamomile Botanicals Bundle for calm and stress support for bath and body.


For Help with Stress-Induced Pain

Part of managing daily stress is addressing the aches and pains that can come along with it. You can take the new Calming Capsules but also add a few of the topical pain-relieving solutions to your routine. Here are the ones that contain helpful pain-fighting ingredients along with the trusted CBD formulas you love: CBD Relief and Recovery including Freeze roll-on, Relieve spray, and Recover cream.

Follow cbdMD’s Blog for More Information

One reason we have created Calming Capsules is that the combination of saffron, ashwagandha, and CBD seems to address a lot of the combined concerns mentioned above. If you are already taking a CBD product you love, you can also take the Calming Capsules for additional support.

For more information on SaffSerene, Sensoril, CBD, or other botanical solutions for your everyday concerns, visit our website or follow our blog. We’ll keep you up to date on all things CBD, on SaffSerene benefits for your life, and on any new ingredients, we add to our selections of calming products.

*Note, consult with a practitioner if taking antidepressant. As always, speak with a qualified healthcare practitioner before consuming any new supplements*